Download and read online Biomaterials in PDF and EPUB Intended for use in an introductory course on biomaterials, taught primarily in departments of biomedical engineering. The book covers classes of materials commonly used in biomedical applications, followed by coverage of the biocompatibility of those materials with the biological environment. Finally, it covers some in-depth applications of biomaterials. It does all of this with an overall emphasis on tissue engineering.
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Download and read online Mimicking the Extracellular Matrix in PDF and EPUB The extracellular matrix (ECM) is the focus of much interest in biology and bioengineering. Increasing understanding of the influence of the ECM on cell behaviour has led to the exciting possibilities of tissue engineering. Aside from new therapeutic tools, understanding the ECM is of course fundamental to basic cell biology research. Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Seven topics are approached each in a pair of chapters, one with a biological approach and its partner with a bioengineering approach. Topics include the mechanical properties of the ECM, which outlines current knowledge of the ECM physical structure and reviewing state-of-the-art strategies to mimic its native microenvironments. The organisational characteristics of the ECM form the focus of another pair of chapters, where the collagen triple helix is discussed, followed by a review of advances in artificial reproduction of well-ordered systems using self-assembling peptides, or peptide amphiphiles. The balanced approach of this text gives it a broad appeal to those interested in the ECM from a range of backgrounds and disciplines. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials.
Download and read online Introduction to Biomaterials in PDF and EPUB A succinct introduction to the field of biomaterials engineering, packed with practical insights.
Download and read online Biomaterials Science in PDF and EPUB The revised edition of this renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. Over 29,000 copies sold, this is the most comprehensive coverage of principles and applications of all classes of biomaterials: "the only such text that currently covers this area comprehensively" - Materials Today Edited by four of the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and expanded, key new topics include of tissue engineering, drug delivery systems, and new clinical applications, with new teaching and learning material throughout, case studies and a downloadable image bank
Download and read online Introduction to Statistics for Biomedical Engineers in PDF and EPUB There are many books written about statistics, some brief, some detailed, some humorous, some colorful, and some quite dry. Each of these texts is designed for a specific audience. Too often, texts about statistics have been rather theoretical and intimidating for those not practicing statistical analysis on a routine basis. Thus, many engineers and scientists, who need to use statistics much more frequently than calculus or differential equations, lack sufficient knowledge of the use of statistics. The audience that is addressed in this text is the university-level biomedical engineering student who needs a bare-bones coverage of the most basic statistical analysis frequently used in biomedical engineering practice. The text introduces students to the essential vocabulary and basic concepts of probability and statistics that are required to perform the numerical summary and statistical analysis used in the biomedical field. This text is considered a starting point for important issues to consider when designing experiments, summarizing data, assuming a probability model for the data, testing hypotheses, and drawing conclusions from sampled data. A student who has completed this text should have sufficient vocabulary to read more advanced texts on statistics and further their knowledge about additional numerical analyses that are used in the biomedical engineering field but are beyond the scope of this text. This book is designed to supplement an undergraduate-level course in applied statistics, specifically in biomedical engineering. Practicing engineers who have not had formal instruction in statistics may also use this text as a simple, brief introduction to statistics used in biomedical engineering. The emphasis is on the application of statistics, the assumptions made in applying the statistical tests, the limitations of these elementary statistical methods, and the errors often committed in using statistical analysis. A number of examples from biomedical engineering research and industry practice are provided to assist the reader in understanding concepts and application. It is beneficial for the reader to have some background in the life sciences and physiology and to be familiar with basic biomedical instrumentation used in the clinical environment. Contents: Introduction / Collecting Data and Experimental Design / Data Summary and Descriptive Statistics / Assuming a Probability Model from the Sample Data / Statistical Inference / Linear Regression and Correlation Analysis / Power Analysis and Sample Size / Just the Beginning / Bibliography
Download and read online Numerical Methods in Biomedical Engineering in PDF and EPUB Numerical Modeling in Biomedical Engineering brings together the integrative set of computational problem solving tools important to biomedical engineers. Through the use of comprehensive homework exercises, relevant examples and extensive case studies, this book integrates principles and techniques of numerical analysis. Covering biomechanical phenomena and physiologic, cell and molecular systems, this is an essential tool for students and all those studying biomedical transport, biomedical thermodynamics & kinetics and biomechanics. Supported by Whitaker Foundation Teaching Materials Program; ABET-oriented pedagogical layout Extensive hands-on homework exercises
Download and read online Biodesign in PDF and EPUB Recognize market opportunities, master the design process, and develop business acumen with this 'how-to' guide to medical technology innovation. Outlining a systematic, proven approach for innovation - identify, invent, implement - and integrating medical, engineering, and business challenges with real-world case studies, this book provides a practical guide for students and professionals.
Download and read online Numerical and Statistical Methods for Bioengineering in PDF and EPUB The first MATLAB-based numerical methods textbook for bioengineers that uniquely integrates modelling concepts with statistical analysis, while maintaining a focus on enabling the user to report the error or uncertainty in their result. Between traditional numerical method topics of linear modelling concepts, nonlinear root finding, and numerical integration, chapters on hypothesis testing, data regression and probability are interweaved. A unique feature of the book is the inclusion of examples from clinical trials and bioinformatics, which are not found in other numerical methods textbooks for engineers. With a wealth of biomedical engineering examples, case studies on topical biomedical research, and the inclusion of end of chapter problems, this is a perfect core text for a one-semester undergraduate course.
Download and read online Statistics for Bioengineering Sciences in PDF and EPUB Through its scope and depth of coverage, this book addresses the needs of the vibrant and rapidly growing engineering fields, bioengineering and biomedical engineering, while implementing software that engineers are familiar with. The author integrates introductory statistics for engineers and introductory biostatistics as a single textbook heavily oriented to computation and hands on approaches. For example, topics ranging from the aspects of disease and device testing, Sensitivity, Specificity and ROC curves, Epidemiological Risk Theory, Survival Analysis, or Logistic and Poisson Regressions are covered. In addition to the synergy of engineering and biostatistical approaches, the novelty of this book is in the substantial coverage of Bayesian approaches to statistical inference. Many examples in this text are solved using both the traditional and Bayesian methods, and the results are compared and commented.
Download and read online Culture of Animal Cells in PDF and EPUB Since the publication of the sixth edition of this benchmark text, numerous advances in the field have been made – particularly in stem cells, 3D culture, scale-up, STR profiling, and culture of specialized cells. Culture of Animal Cells: A Manual of Basic Technique and Specialized Applications, Seventh Edition is the updated version of this benchmark text, addressing these recent developments in the field as well as the basic skills and protocols. This eagerly awaited edition reviews the increasing diversity of the applications of cell culture and the proliferation of specialized techniques, and provides an introduction to new subtopics in mini-reviews. New features also include a new chapter on cell line authentication with a review of the major issues and appropriate protocols including DNA profiling and barcoding, as well as some new specialized protocols. Because of the continuing expansion of cell culture, and to keep the bulk of the book to a reasonable size, some specialized protocols are presented as supplementary material online. Culture of Animal Cells: A Manual of Basic Technique and Specialized Applications, Seventh Edition provides the most accessible and comprehensive introduction available to the culture and experimental manipulation of animal cells. This text is an indispensable resource for those in or entering the field, including academic research scientists, clinical and biopharmaceutical researchers, undergraduate and graduate students, cell and molecular biology and genetics lab managers, trainees and technicians.
Download and read online Biological Interactions on Materials Surfaces in PDF and EPUB Success or failure of biomaterials, whether tissue engineered constructs, joint and dental implants, vascular grafts, or heart valves, depends on molecular-level events that determine subsequent responses of cells and tissues. This book presents the latest developments and state-of-the-art knowledge regarding protein, cell, and tissue interactions with both conventional and nanophase materials. Insight into these biomaterial surface interactions will play a critical role in further developments in fields such as tissue engineering, regenerative medicine, and biocompatibility of implanted materials and devices. With chapters written by leaders in their respective fields, this compendium will be the authoritative source of information for scientists, engineers, and medical researchers seeking not only to understand but also to control tissue-biomaterial interactions.
Download and read online Quantitative Human Physiology in PDF and EPUB Quantitative Human Physiology: An Introduction is the first text to meet the needs of the undergraduate bioengineering student who is being exposed to physiology for the first time, but requires a more analytical/quantitative approach. This book explores how component behavior produces system behavior in physiological systems. Through text explanation, figures, and equations, it provides the engineering student with a basic understanding of physiological principles with an emphasis on quantitative aspects. Features a quantitative approach that includes physical and chemical principles Provides a more integrated approach from first principles, integrating anatomy, molecular biology, biochemistry and physiology Includes clinical applications relevant to the biomedical engineering student (TENS, cochlear implants, blood substitutes, etc.) Integrates labs and problem sets to provide opportunities for practice and assessment throughout the course NEW FOR THE SECOND EDITION Expansion of many sections to include relevant information Addition of many new figures and re-drawing of other figures to update our understanding and clarify difficult areas Substantial updating of the text to reflect newer research results Addition of several new appendices including statistics, nomenclature of transport carriers, and structural biology of important items such as the neuromuscular junction and calcium release unit Addition of new problems within the problem sets Addition of commentary to power point presentations
Download and read online Receptors in PDF and EPUB Receptors: Models for Binding, Trafficking, and Signaling bridges the gap between chemical engineering and cell biology by lucidly and practically demonstrating how a mathematical modeling approach combined with quantitative experiments can provide enhanced understanding of cell phenomena involving receptor/ligand interactions. In stressing the need for a quantitative understanding of how receptor-mediated cell functions depend on receptor and ligand properties, the book offers comprehensive treatments of both basic and state-of-the-art model frameworks that span the entire spectrum of receptor processes--from fundamental cell surface binding, intracellular trafficking, and signal transduction events to the cell behavioral functions they govern, including proliferation, adhesion, and migration. The book emphasizes mechanistic models that are accessible to experimental testing and includes detailed examples of important contemporary issues. This much-needed book introduces chemical engineers and bioengineers to important problems in receptor biology and familiarizes cell biologists with the insights that can be gained from engineering analysis and synthesis. As such, chemical engineers, researchers, and advanced students in the fields of biotechnology, biomedical sciences, bioengineering, and molecular cell biology will find this book to be conceptually rich, timely, and useful.