How Proteins Work

Filename: how-proteins-work.pdf
ISBN: 9781136665493
Release Date: 2011-07-20
Number of pages: 464
Author: Michael Williamson
Publisher: Garland Science

Download and read online How Proteins Work in PDF and EPUB How Proteins Work is an up-to-date and authoritative account of protein function in living systems, explained within the governing parameters of physics, chemistry, and evolution. This text will enable advanced undergraduate students in biochemistry and biophysics to understand the relationships among protein function, structure, and dynamics. It will also serve as a valuable resource for graduate students and researchers looking for a reference on the fundamentals underlying protein function. By providing an integrated view of proteins at both a cellular and systemic level, this textbook shows how evolution drives proteins to adopt domain structures that combine to achieve biological outcomes. The association of proteins into dimers, molecular machines, and multi-enzymatic complexes enables them to achieve catalytic and functional efficiency.


How Proteins Work

Filename: how-proteins-work.pdf
ISBN: 0815344465
Release Date: 2012
Number of pages: 464
Author: Michael Paul Williamson
Publisher: Garland Pub

Download and read online How Proteins Work in PDF and EPUB How Proteins Work is an up-to-date and authoritative account of protein function in living systems, explained within the governing parameters of physics, chemistry, and evolution. This text will enable advanced undergraduate students in biochemistry and biophysics to understand the relationships among protein function, structure, and dynamics. It will also serve as a valuable resource for graduate students and researchers looking for a reference on the fundamentals underlying protein function. By providing an integrated view of proteins at both a cellular and systemic level, this textbook shows how evolution drives proteins to adopt domain structures that combine to achieve biological outcomes. The association of proteins into dimers, molecular machines, and multi-enzymatic complexes enables them to achieve catalytic and functional efficiency.


Proteins

Filename: proteins.pdf
ISBN: 071677030X
Release Date: 1993-01-01
Number of pages: 507
Author: Thomas E. Creighton
Publisher: Macmillan

Download and read online Proteins in PDF and EPUB In one convenient resource, Creighton's landmark textbook offers an expert introduction to all aspects of proteins--biosynthesis, evolution, structures, dynamics, ligand binding, and catalysis. It works equally well as a reference or as a classroom text.


Molecular Biology of the Cell

Filename: molecular-biology-of-the-cell.pdf
ISBN: 9781317563747
Release Date: 2017-08-07
Number of pages: 1464
Author: Bruce Alberts
Publisher: Garland Science

Download and read online Molecular Biology of the Cell in PDF and EPUB As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.


Essential Cell Biology Fourth Edition

Filename: essential-cell-biology-fourth-edition.pdf
ISBN: 9781317806271
Release Date: 2013-10-15
Number of pages: 865
Author: Bruce Alberts
Publisher: Garland Science

Download and read online Essential Cell Biology Fourth Edition in PDF and EPUB Essential Cell Biology provides a readily accessible introduction to the central concepts of cell biology, and its lively, clear writing and exceptional illustrations make it the ideal textbook for a first course in both cell and molecular biology. The text and figures are easy-to-follow, accurate, clear, and engaging for the introductory student. Molecular detail has been kept to a minimum in order to provide the reader with a cohesive conceptual framework for the basic science that underlies our current understanding of all of biology, including the biomedical sciences. The Fourth Edition has been thoroughly revised, and covers the latest developments in this fast-moving field, yet retains the academic level and length of the previous edition.


Soliton Theory

Filename: soliton-theory.pdf
ISBN: 0719014913
Release Date: 1990-01-01
Number of pages: 449
Author: Allan P. Fordy
Publisher: Manchester University Press

Download and read online Soliton Theory in PDF and EPUB A coherent introduction to the complete range of soliton theory including Hirota's method and Backlund transformations. Details physical applications of soliton theory with chapters on the peculiar wave patterns of the Andaman Sea, atmospheric phenomena, general relativity and Davydov solitons. Contains testing for full integrability, a discussion of the Painlevé technique, symmetries and conservation law.


Nature s Robots

Filename: nature-s-robots.pdf
ISBN: 9780191578519
Release Date: 2003-11-27
Number of pages: 312
Author: Charles Tanford
Publisher: OUP Oxford

Download and read online Nature s Robots in PDF and EPUB Proteins are amazingly versatile molecules. They make the chemical reactions happen that form the basis for life, they transmit signals in the body, they identify and kill foreign invaders, they form the engines that make us move, and they record visual images. All of this is now common knowledge, but it was not so a hundred years ago. Nature's Robots is an authoritative history of protein science, from the origins of protein research in the nineteenth century, when the chemical constitution of 'protein' was first studied and heatedly debated and when there was as yet no glimmer of the functional potential of substances in the 'protein' category, to the determination of the first structures of individual proteins at atomic resolution - when positions of individual atoms were first specified exactly and bonding between neighbouring atoms precisely defined. Tanford and Reynolds, who themselves made major contributions to the golden age of protein science, have written a remarkably vivid account of this history. It is a fascinating story, involving heroes from the past, working mostly alone or in small groups, usually with little support from formal research groups. It is also a story that embraces a number of historically important scientific controversies. Written in clear and accessible prose, Nature's Robots will appeal to general readers with an interest in popular science, in addition to professional scientists and historians of science.


Localization Energy Transfer in Nonlinear Systems

Filename: localization-energy-transfer-in-nonlinear-systems.pdf
ISBN: 9812704620
Release Date: 2003
Number of pages: 351
Author: Robert Sinclair MacKay
Publisher: World Scientific

Download and read online Localization Energy Transfer in Nonlinear Systems in PDF and EPUB This conference was the third meeting organized in the framework of the European LOCNET project. The main topics discussed by this international research collaboration were localization by nonlinearity and spatial discreteness, and energy transfer (in crystals, biomolecules and Josephson arrays).


A Positron Named Priscilla

Filename: a-positron-named-priscilla.pdf
ISBN: 9780309048934
Release Date: 1994-01-01
Number of pages: 360
Author: Addison Greenwood
Publisher: National Academies Press

Download and read online A Positron Named Priscilla in PDF and EPUB A Positron Named Priscilla is a book of wonder, offering a fascinating, readable overview of cutting-edge investigations by many of today's leading young scientists. Written for anyone who loves science, this volume reports on some of the most exciting recent discoveries and advances in fields from astronomy to molecular biology. This new book is from one of the world's most prestigious scientific institutions, the National Academy of Sciences. The Academy provides an annual forum for the brightest young investigators to exchange ideas across disciplines--an exchange that was the spark for A Positron Named Priscilla. Each chapter is authored by a popular science writer who offers helpful historical perspectives, clear and well-illustrated explanations of current scientific thinking, and previews of future developments. The scope of topics and breadth of discussion ensure interest at all levels. Topics include Planetary science and the compelling glimpse through the clouded atmosphere of Venus afforded by the spacecraft Magellan. Astrophysics and the emergence of helioseismology, a new field that allows researchers to probe the interior workings of the sun. Biology and what we have learned about DNA in the 40 years since its discovery; our current understanding of protein molecules, the "building blocks" of living systems; and the high-tech search for answers to the AIDS epidemic. Physics and our new-found ability to move and manipulate individual atoms on a surface. The book also tells the remarkable story of "buckyballs," or buckminsterfullerenes, a form of carbon discovered only a few years ago, that have the potential to be used in a variety of important applications, from superconductivity to nanotechnology. Mathematics and the rise of "wavelet" theory, and how mathematicians are applying it in sometimes startling ways, from assisting the FBI with fingerprint storage to coaxing the secrets from a battered recording of Brahms playing the piano. Geosciences and the search for "clocks in the earth" to make life-saving earthquake predictions. A Positron Named Priscilla is a "must" read for anyone who wants to keep up with a broad range of scientific endeavor.


Translation Mechanisms

Filename: translation-mechanisms.pdf
ISBN: 0306478390
Release Date: 2003-07-31
Number of pages: 468
Author: Jacques Lapointe
Publisher: Springer Science & Business Media

Download and read online Translation Mechanisms in PDF and EPUB Translation Mechanisms provides investigators and graduate students with overviews of recent developments in the field of protein biosynthesis that are fuelled by the explosive and synergic growth of structural biology, genomics, and bioinformatics. The outstanding progress in our understanding of the structure, dynamics, and evolution of the prokaryotic and eukaryotic translation machinery, as well as applications in medicine and biotechnology, are described in 26 chapters covering recent discoveries on: -the subtleties of tRNA aminoacylation with natural and unnatural amino acids. -the control of mRNA stability, a key step of gene regulation. -ribosome structure and function, in the era of the atomic-crystal resolution of the ribosome. -the regulation of the biosynthesis of the translational machinery components. -the action of a variety of inhibitors of translation and the prospect for clinical studies.


One Plus One Equals One

Filename: one-plus-one-equals-one.pdf
ISBN: 9780191636288
Release Date: 2014-06-26
Number of pages: 288
Author: John Archibald
Publisher: OUP Oxford

Download and read online One Plus One Equals One in PDF and EPUB We are in the midst of a revolution. It is a scientific revolution built upon the tools of molecular biology, with which we probe and prod the living world in ways unimaginable a few decades ago. Need to track a bacterium at the root of a hospital outbreak? No problem: the offending germ's complete genetic profile can be obtained in 24 hours. We insert human DNA into E. coli bacteria to produce our insulin. It is natural to look at biotechnology in the 21st century with a mix of wonder and fear. But biotechnology is not as 'unnatural' as one might think. All living organisms use the same molecular processes to replicate their genetic material and the same basic code to 'read' their genes. The similarities can be seen in their DNA. Here, John Archibald shows how evolution has been 'plugging-and-playing' with the subcellular components of life from the very beginning and continues to do so today. For evidence, we need look no further than the inner workings of our own cells. Molecular biology has allowed us to gaze back more than three billion years, revealing the microbial mergers and acquisitions that underpin the development of complex life. One Plus One Equals One tells the story of how we have come to this realization and its implications.


Advances in Blood Substitutes

Filename: advances-in-blood-substitutes.pdf
ISBN: 9781461219767
Release Date: 2012-12-06
Number of pages: 336
Author: R. Winslow
Publisher: Springer Science & Business Media

Download and read online Advances in Blood Substitutes in PDF and EPUB Each chapter of this volume is a contribution from an expert in the field, chosen by the editors to contribute to the 1997 "Current Issues in Blood Substitute Research and Development" course given in San Diego, March 17-19. The contributors were selected because of their expertise in areas which the editors believe to be critical to the advancement of the field, and which reflect activity in "hot" areas of relevant research. While there is a continuity in style for the annual course, each year brings changes in emphasis and content. In previous years, we were often not able to provide time for participants to present their views and opinions. Consequently, this year we encouraged discussion after each presentation. These sessions were recorded, transcribed, and are printed with the chapters herein. We believe that the product is very close to the capturing this year's course in print, and trust readers will enjoy reading the always candid and often provocative remarks from the audience. The price paid for inclusion of the discussion transcriptions was a delay in publication. Each author was allowed to edit his/her discussion section as well as the final version of the chapters prior to publication. The changes are mainly for grammar, and we tried, when possible, not to alter the conversational style of these interchanges.


Introduction to Protein Structure

Filename: introduction-to-protein-structure.pdf
ISBN: 9780815323051
Release Date: 1999
Number of pages: 410
Author: Carl-Ivar Brändén
Publisher: Taylor & Francis

Download and read online Introduction to Protein Structure in PDF and EPUB This new edition gives an up-to-date account of the principles of protein structure, with examples of key proteins in their biological context, illustrated in colour to illuminate the structural principles described in the text.


Non Natural Amino Acids

Filename: non-natural-amino-acids.pdf
ISBN: 0080921639
Release Date: 2009-07-24
Number of pages: 350
Author:
Publisher: Academic Press

Download and read online Non Natural Amino Acids in PDF and EPUB By combining the tools of organic chemistry with those of physical biochemistry and cell biology, Non-Natural Amino Acids aims to provide fundamental insights into how proteins work within the context of complex biological systems of biomedical interest. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. With more than 400 volumes published, each Methods in Enzymology volume presents material that is relevant in today's labs -- truly an essential publication for researchers in all fields of life sciences. Demonstrates how the tools and principles of chemistry combined with the molecules and processes of living cells can be combined to create molecules with new properties and functions found neither in nature nor in the test tube Presents new insights into the molecular mechanisms of complex biological and chemical systems that can be gained by studying the structure and function of non-natural molecules Provides a "one-stop shop" for tried and tested essential techniques, eliminating the need to wade through untested or unreliable methods


Anatomy and Physiology

Filename: anatomy-and-physiology.pdf
ISBN: 9780323316873
Release Date: 2015-02-10
Number of pages: 1264
Author: Kevin T. Patton
Publisher: Elsevier Health Sciences

Download and read online Anatomy and Physiology in PDF and EPUB Anatomy and Physiology