Download and read online Introducing Epigenetics in PDF and EPUB Epigenetics is the most exciting field in biology today, developing our understanding of how and why we inherit certain traits, develop diseases and age, and evolve as a species. This non-fiction comic book introduces us to genetics, cell biology and the fascinating science of epigenetics, which is rapidly filling in the gaps in our knowledge, allowing us to make huge advances in medicine. We’ll look at what identical twins can teach us about the epigenetic effects of our environment and experiences, why certain genes are 'switched on' or off at various stages of embryonic development, and how scientists have reversed the specialization of cells to clone frogs from a single gut cell. In Introducing Epigenetics, Cath Ennis and Oliver Pugh pull apart the double helix, examining how the epigenetic building blocks and messengers that interpret and edit our genes help to make us, well, us.
Download and read online Introducing Epigenetics in PDF and EPUB Introducing Graphic Guide to the most exciting field in biology today, Epigenetics.
Download and read online Introducing Game Theory in PDF and EPUB When should you adopt an aggressive business strategy? How do we make decisions when we don’t have all the information? What makes international environmental cooperation possible? Game theory is the study of how we make a decision when the outcome of our moves depends on the decisions of someone else. Economists Ivan and Tuvana Pastine explain why, in these situations, we sometimes cooperate, sometimes clash, and sometimes act in a way that seems completely random. Stylishly brought to life by award-winning cartoonist Tom Humberstone, Game Theory will help readers understand behaviour in everything from our social lives to business, global politics to evolutionary biology. It provides a thrilling new perspective on the world we live in.
Download and read online Epigenetics How Environment Shapes Our Genes in PDF and EPUB Goodbye, genetic blueprint. . . . The first book for general readers on the game-changing field of epigenetics. The burgeoning new science of epigenetics offers a cornucopia of insights—some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.
Download and read online The Epigenetics Revolution in PDF and EPUB Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism’s genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field’s arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.
Download and read online The Developing Genome in PDF and EPUB Why do we grow up to look, act, and feel as we do? Through most of the twentieth century, scientists and laypeople answered this question by referring to two factors alone: our experiences and our genes. But recent discoveries about how genes work have revealed a new way to understand the developmental origins of our characteristics. These discoveries have emerged from the new science of behavioral epigenetics--and just as the whole world has now heard of DNA, "epigenetics" will be a household word in the near future. Behavioral epigenetics is important because it explains how our experiences get under our skin and influence the activity of our genes. Because of breakthroughs in this field, we now know that the genes we're born with don't determine if we'll end up easily stressed, likely to fall ill with cancer, or possessed of a powerful intellect. Instead, what matters is what our genes do. And because research in behavioral epigenetics has shown that our experiences influence how our genes function, this work has changed how scientists think about nature, nurture, and human development. Diets, environmental toxins, parenting styles, and other environmental factors all influence genetic activity through epigenetic mechanisms; this discovery has the potential to alter how doctors treat diseases, and to change how mental health professionals treat conditions from schizophrenia to post-traumatic stress disorder. These advances could also force a reworking of the theory of evolution that dominated twentieth-century biology, and even change how we think about human nature itself. In spite of the importance of this research, behavioral epigenetics is still relatively unknown to non-biologists. The Developing Genome is an introduction to this exciting new discipline; it will allow readers without a background in biology to learn about this work and its revolutionary implications.
Download and read online Evolution in Four Dimensions revised edition in PDF and EPUB A pioneering proposal for a pluralistic extension of evolutionary theory, now updated to reflect the most recent research.
Download and read online Junk DNA in PDF and EPUB From the author of the acclaimed The Epigenetics Revolution (‘A book that would have had Darwin swooning’ – Guardian) comes another thrilling exploration of the cutting edge of human science. For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions – 98% of the human genome – were dismissed as ‘junk’. But in recent years researchers have discovered that variations in this ‘junk’ DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself – and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.
Download and read online Epigenetic Gene Expression and Regulation in PDF and EPUB Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring Chapters are replete with clinical examples to empower the basic biology with translational significance Offers more than 100 illustrations to distill key concepts and decipher complex science
Download and read online Epigenetics in PDF and EPUB The book EPIGENETICS is a global update of Darwin's book The Origin of Species. There is no other book that embraces all of the events (political, socially, biologically, nutritionally, chemically and genetically) that have been spawned since the publication of The Origin of Species by Darwin more than 100 years ago. EPIGENETICS is required reading for the very survival of Americans and yes all of humanity - modern man has bet on the wrong horse to save them from disease and pestilence - the medical system has failed us fearfully. It is predictable that this book will impact the world of the everyday man, science, politics, social engineering and medicine to the same degree that Darwin's The Origin of Species did more than 100 years ago. This book will be welcomed and enjoyed by religious leaders, community leaders, educators, parents and students of biology, nutrients and genetics in all forms. The general public will obviously be the larger market. Dr. Wallach has been lecturing 300 times per year to national and international audiences for more than 20 years. Dr.s Wallach and Ma have 10 best- selling books that were self-published (the best known Dead Doctors Don't Lie -hundreds of thousands sold - a favorite with Amazon.com) and dozens of CD titles - the most listened to of which is Dead Doctors Don't Lie which has sold just short of 200 million copies - Dr. Wallach's audience is very large and very loyal. Historically, Wallach's audiences range from 100 to 500 people, however, in the last 10 years enlarged by simulcast technology his audiences can range into the tens of thousands. For 18 years, Dr. Wallach has been the host of two one hour interactive radio talk shows that air M-F from 12:00 - 2:00 PST. Since 2011 Wallach has also been allied with the GCN radio network that has 1,342 stations.
Download and read online Introducing Machiavelli in PDF and EPUB Illustrated guide to the crucial Italian philosopher and author of The Prince. 'Machiavellian' is a popular byword for treachery and opportunism. Machiavelli's classic book on statecraft, The Prince, published over 400 years ago, remains controversial to this day because of its electrifying frankness as a practical guide to power. Is it a how-to manual for dictators, a cynical philosophy of 'the end justifies the means', or a more complex and subtle analysis of successful government? Machiavelli was a loyal servant of the Florentine republic. His opposition to Medici despotism led him to torture on the rack and exile, and yet he chose as his model for the Prince the most notorious tyrant, Cesare Borgia. Introducing Machiavelli traces the colourful life of this paradoxical realist whose clear-sighted patriotism made him the first truly modern political scientist. Machiavelli is seen as central to the postmodern debate on Civil Society. This book brings the creative turbulence of Renaissance Italy to life, and presents a compelling portrait of a key figure of European political history.
Download and read online We Have No Idea in PDF and EPUB Prepare to learn everything we still don’t know about our strange, mostly mysterious universe. PHD Comics creator Jorge Cham and particle physicist Daniel Whiteson have teamed up to spelunk through the enormous gaps in our cosmological knowledge, armed with their popular infographics, cartoons, and unusually entertaining and lucid explanations of science. In We Have No Idea, they explore the biggest unknowns in the universe, why these things are still mysteries, and what a lot of smart people are doing to figure out the answers (or at least ask the right questions). While they're at it, they helpfully demystify many complicated things we do know about, from quarks and neutrinos to gravitational waves and exploding black holes. With equal doses of humor and delight, they invite us to see the universe as a vast expanse of mostly uncharted territory that's still ours to explore. This entertaining illustrated science primer is the perfect book for anyone who's curious about all the big questions physicists are still trying to answer. From the Hardcover edition.
Download and read online Herding Hemingway s Cats in PDF and EPUB The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work? There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the 'recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. Figuring out how it all works Â? how your genes build your body Â? is a major challenge for researchers around the world. And what they're discovering is that far from genes being a fixed, deterministic blueprint, things are much more random and wobbly than anyone expected. Drawing on stories ranging from six toed cats and stickleback hips to Mickey Mouse mice and zombie genes Â? told by researchers working at the cutting edge of genetics Â? Kat Arney explores the mysteries in our genomes with clarity, flair and wit, creating a companion reader to the book of life itself.
Download and read online Introducing Hinduism in PDF and EPUB "Introducing Hinduism" offers a guide to the key philosophical, literary, mythological and cultural traditions of this extraordinarily diverse faith. It untangles the complexities of Hinduism's gods and goddesses, its caste system and its views on sex, everyday life and asceticism. This work answers questions including: Why do Hindus revere the cow? Must Hindus be vegetarian? And much more...
Download and read online Epigenetics in PDF and EPUB "The concept of epigenetics has been known about since the 1940s, but it is only in the last 10 years that research has shown just how wide ranging its effects are. It is now a very widely-used term, but there is still a lot of confusion surrounding what it actually is and does. Epigenetics brings together the structure and machinery of epigenetic modification, how epigenetic modification controls cellular functions, and the evidence for the relationship between epigenetics and disease. It will therefore be an invaluable source of information about all aspects of this subject for undergraduate students, graduate students, and professionals alike. Topics included are the role of epigenetics in stem cells, the involvement of epigenetics with cancer, and the role of epigenetics in mental health. Key Features - Describes the two forms of epigenetic modification, DNA methylation and histone acetylation, and how they take place. - Section on how epigenetics controls cell function, including cellular differentiation and consequently the role of epigenetics in stem cells - Section on the role of epigenetics in disease only includes diseases where there is clear evidence of epigenetic involvement - Glossary explaining all the terms involved in epigenetics - Full-color figures"--Provided by publisher.