Junk DNA

Filename: junk-dna.pdf
ISBN: 9781848318267
Release Date: 2015-03-05
Number of pages: 288
Author: Nessa Carey
Publisher: Icon Books

Download and read online Junk DNA in PDF and EPUB From the author of the acclaimed The Epigenetics Revolution (‘A book that would have had Darwin swooning’ – Guardian) comes another thrilling exploration of the cutting edge of human science. For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions – 98% of the human genome – were dismissed as ‘junk’. But in recent years researchers have discovered that variations in this ‘junk’ DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself – and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.


Junk DNA

Filename: junk-dna.pdf
ISBN: 9780231539418
Release Date: 2015-03-10
Number of pages: 224
Author: Nessa Carey
Publisher: Columbia University Press

Download and read online Junk DNA in PDF and EPUB For decades after identifying the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98% of the human genome were dismissed as “junk,” sequences that serve no purpose. Yet recently researchers have discovered variations and modulations in this junk DNA that underwrite a number of intractable diseases. This knowledge has led to innovative research and treatment approaches that may finally control these conditions. Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. Its function has forced scientists to revisit the very meaning of the word “gene” and has engendered a bitter battle over whether or not this genomic “nonsense” is the source of human biological complexity. Drawing on her experience with leading investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, disease treatments, and evolution. We are only now unlocking the secrets of junk DNA, and Carey’s book is an indispensable resource for navigating the codes and controversies of this fast-growing and hotly disputed field.


Junk DNA

Filename: junk-dna.pdf
ISBN: 9781848318274
Release Date: 2015-03-05
Number of pages: 288
Author: Nessa Carey
Publisher: Icon Books Ltd

Download and read online Junk DNA in PDF and EPUB From the author of the acclaimed The Epigenetics Revolution (‘A book that would have had Darwin swooning’ – Guardian) comes another thrilling exploration of the cutting edge of human science. For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions – 98% of the human genome – were dismissed as ‘junk’. But in recent years researchers have discovered that variations in this ‘junk’ DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself – and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.


The Epigenetics Revolution

Filename: the-epigenetics-revolution.pdf
ISBN: 9780231530712
Release Date: 2012-03-06
Number of pages: 352
Author: Nessa Carey
Publisher: Columbia University Press

Download and read online The Epigenetics Revolution in PDF and EPUB Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism’s genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field’s arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.


The Myth of Junk DNA

Filename: the-myth-of-junk-dna.pdf
ISBN: 1936599007
Release Date: 2011
Number of pages: 170
Author: Jonathan Wells
Publisher: Discovery Inst

Download and read online The Myth of Junk DNA in PDF and EPUB According to the modern version of Darwin's theory, DNA contains a program for embryo development that is passed down from generation to generation; the program is implemented by proteins encoded by the DNA, and accidental DNA mutations introduce changes in those proteins that natural selection then shapes into new species, organs and body plans. When scientists discovered forty years ago that about 98% of our DNA does not encode proteins, the non-protein-coding portion was labeled “junk” and attributed to molecular accidents that have accumulated in the course of evolution. Recent books by Richard Dawkins, Francis Collins and others have used this “junk DNA” as evidence for Darwinian evolution and evidence against intelligent design (since an intelligent designer would presumably not have filled our genome with so much garbage). But recent genome evidence shows that much of our non-protein-coding DNA performs essential biological functions. The Myth of Junk DNA is written for a general audience by biologist Jonathan Wells, author of Icons of Evolution. Citing some of the abundant evidence from recent genome projects, the book shows that “junk DNA” is not science, but myth.


The Mysterious Epigenome

Filename: the-mysterious-epigenome.pdf
ISBN: 9780825488825
Release Date: 2011-12-01
Number of pages: 160
Author: Thomas Woodward
Publisher: Kregel Publications

Download and read online The Mysterious Epigenome in PDF and EPUB In this creative and inventive treatment, authors Thomas E. Woodward and James P. Gills take readers on an exploration of the human epigenome. Acting as tour guides leading visitors through a 3-D model of a human cell, Woodward and Gills bring to life the human molecular makeup. Readers (as visitors) will get up close and personal with the minute details of human molecular structure, including E. coli, flagellum, a DNA helix, an RNA molecule, and more. By seeing it with their own eyes, readers will gain a better understanding of their genetic systems and a better appreciation for the Creator who put this all into place.


Virolution

Filename: virolution.pdf
ISBN: 9780007545278
Release Date: 2013-11-28
Number of pages: 400
Author: Frank Ryan
Publisher: HarperCollins UK

Download and read online Virolution in PDF and EPUB The extraordinary role of viruses in evolution and how this is revolutionising biology and medicine.


Life s Greatest Secret

Filename: life-s-greatest-secret.pdf
ISBN: 9781782830023
Release Date: 2015-06-11
Number of pages: 728
Author: Matthew Cobb
Publisher: Profile Books

Download and read online Life s Greatest Secret in PDF and EPUB Life's Greatest Secret is the story of the discovery and cracking of the genetic code. This great scientific breakthrough has had far-reaching consequences for how we understand ourselves and our place in the natural world. The code forms the most striking proof of Darwin's hypothesis that all organisms are related, holds tremendous promise for improving human well-being, and has transformed the way we think about life. Matthew Cobb interweaves science, biography and anecdote in a book that mixes remarkable insights, theoretical dead-ends and ingenious experiments with the pace of a thriller. He describes cooperation and competition among some of the twentieth century's most outstanding and eccentric minds, moves between biology, physics and chemistry, and shows the part played by computing and cybernetics. The story spans the globe, from Cambridge MA to Cambridge UK, New York to Paris, London to Moscow. It is both thrilling science and a fascinating story about how science is done.


Introducing Epigenetics

Filename: introducing-epigenetics.pdf
ISBN: 9781848319035
Release Date: 2017-02-02
Number of pages: 176
Author: Cath Ennis
Publisher: Icon Books Ltd

Download and read online Introducing Epigenetics in PDF and EPUB Epigenetics is the most exciting field in biology today, developing our understanding of how and why we inherit certain traits, develop diseases and age, and evolve as a species. This non-fiction comic book introduces us to genetics, cell biology and the fascinating science of epigenetics, which is rapidly filling in the gaps in our knowledge, allowing us to make huge advances in medicine. We’ll look at what identical twins can teach us about the epigenetic effects of our environment and experiences, why certain genes are 'switched on' or off at various stages of embryonic development, and how scientists have reversed the specialization of cells to clone frogs from a single gut cell. In Introducing Epigenetics, Cath Ennis and Oliver Pugh pull apart the double helix, examining how the epigenetic building blocks and messengers that interpret and edit our genes help to make us, well, us.


A Brief History of Fayetteville Arkansas

Filename: a-brief-history-of-fayetteville-arkansas.pdf
ISBN: 9781625857736
Release Date: 2017-04-03
Number of pages: 160
Author: Charles Y. Alison
Publisher: Arcadia Publishing

Download and read online A Brief History of Fayetteville Arkansas in PDF and EPUB Originally a small town called Washington Courthouse, Fayetteville bloomed into one of Arkansas’s largest cities. The town prospered during its first two decades, until it suffered decimation during the Civil War as troops moved throughout the region. In 1871, Fayetteville successfully bid to be home to the University of Arkansas, the state’s first public university. Today, the city represents a cultural convergence, with remnants of historic trails such as the Military Road between St. Louis and Fort Smith and the Trail of Tears. Author and historian Charlie Alison details pivotal events that shaped the city.


Epigenetics How Environment Shapes Our Genes

Filename: epigenetics-how-environment-shapes-our-genes.pdf
ISBN: 9780393080322
Release Date: 2011-06-13
Number of pages: 256
Author: Richard C. Francis
Publisher: W. W. Norton & Company

Download and read online Epigenetics How Environment Shapes Our Genes in PDF and EPUB Goodbye, genetic blueprint. . . . The first book for general readers on the game-changing field of epigenetics. The burgeoning new science of epigenetics offers a cornucopia of insights—some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.


Frankenstein s Cat

Filename: frankenstein-s-cat.pdf
ISBN: 9781780742168
Release Date: 2013-01-03
Number of pages: 256
Author: Emily Anthes
Publisher: Oneworld Publications

Download and read online Frankenstein s Cat in PDF and EPUB From the petri dish to the pet shop, meet the high-tech menagerie of the near future, as humans reinvent the animal kingdom Fluorescent fish that glow near pollution. Dolphins with prosthetic fins. Robot-armoured beetles that military handlers can send on spy missions. Beloved pet pigs resurrected from DNA. Scientists have already begun to create these high-tech hybrids to serve human whims and needs. What if a cow could be engineered to no longer feel pain – should we design a herd that would assuage our guilt over eating meat? Acclaimed science writer Emily Anthes travels round the globe to meet the fauna of the future, from the Scottish birthplace of Dolly the sheep and other clones to a ‘pharm’ for cancer-fighting chickens. Frankenstein’s Cat is an eye-opening exploration of weird science – and how we are playing god in the animal world.


Herding Hemingway s Cats

Filename: herding-hemingway-s-cats.pdf
ISBN: 9781472910066
Release Date: 2016-01-14
Number of pages: 288
Author: Kat Arney
Publisher: Bloomsbury Publishing

Download and read online Herding Hemingway s Cats in PDF and EPUB The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work? There are 2.2 metres of DNA inside every one of your cells, encoding roughly 20,000 genes. These are the 'recipes' that tell our cells how to make the building blocks of life, along with myriad control switches ensuring they're turned on and off at the right time and in the right place. But rather than a static string of genetic code, this is a dynamic, writhing biological library. Figuring out how it all works Â? how your genes build your body Â? is a major challenge for researchers around the world. And what they're discovering is that far from genes being a fixed, deterministic blueprint, things are much more random and wobbly than anyone expected. Drawing on stories ranging from six toed cats and stickleback hips to Mickey Mouse mice and zombie genes Â? told by researchers working at the cutting edge of genetics Â? Kat Arney explores the mysteries in our genomes with clarity, flair and wit, creating a companion reader to the book of life itself.


Gene Cloning and DNA Analysis

Filename: gene-cloning-and-dna-analysis.pdf
ISBN: 9781119072546
Release Date: 2015-10-13
Number of pages: 376
Author: T. A. Brown
Publisher: John Wiley & Sons

Download and read online Gene Cloning and DNA Analysis in PDF and EPUB Known world-wide as the standard introductory text to this important and exciting area, the seventh edition of Gene Cloning and DNA Analysis addresses new and growing areas of research whilst retaining the philosophy of the previous editions. Assuming the reader has little prior knowledge of the subject, its importance, the principles of the techniques used and their applications are all carefully laid out, with over 250 clearly presented four-colour illustrations. In addition to a number of informative changes to the text throughout the book, the chapters on DNA sequencing and genome studies have been rewritten to reflect the continuing rapid developments in this area of DNA analysis: In depth description of the next generation sequencing methods and descriptions of their applications in studying genomes and transcriptomes New material on the use of ChiP-seq to locate protein-binding sites Extended coverage of the strategies used to assemble genome sequences Description of how the Neanderthal genome has been sequenced and what that sequence tells us about interbreeding between Neanderthals and Homo sapiens Gene Cloning and DNA Analysis remains an essential introductory text to a wide range of biological sciences students; including genetics and genomics, molecular biology, biochemistry, immunology and applied biology. It is also a perfect introductory text for any professional needing to learn the basics of the subject. All libraries in universities where medical, life and biological sciences are studied and taught should have copies available on their shelves.


The Developing Genome

Filename: the-developing-genome.pdf
ISBN: 9780199922352
Release Date: 2015-01-29
Number of pages: 272
Author: David S. Moore
Publisher: Oxford University Press

Download and read online The Developing Genome in PDF and EPUB Why do we grow up to look, act, and feel as we do? Through most of the twentieth century, scientists and laypeople answered this question by referring to two factors alone: our experiences and our genes. But recent discoveries about how genes work have revealed a new way to understand the developmental origins of our characteristics. These discoveries have emerged from the new science of behavioral epigenetics--and just as the whole world has now heard of DNA, "epigenetics" will be a household word in the near future. Behavioral epigenetics is important because it explains how our experiences get under our skin and influence the activity of our genes. Because of breakthroughs in this field, we now know that the genes we're born with don't determine if we'll end up easily stressed, likely to fall ill with cancer, or possessed of a powerful intellect. Instead, what matters is what our genes do. And because research in behavioral epigenetics has shown that our experiences influence how our genes function, this work has changed how scientists think about nature, nurture, and human development. Diets, environmental toxins, parenting styles, and other environmental factors all influence genetic activity through epigenetic mechanisms; this discovery has the potential to alter how doctors treat diseases, and to change how mental health professionals treat conditions from schizophrenia to post-traumatic stress disorder. These advances could also force a reworking of the theory of evolution that dominated twentieth-century biology, and even change how we think about human nature itself. In spite of the importance of this research, behavioral epigenetics is still relatively unknown to non-biologists. The Developing Genome is an introduction to this exciting new discipline; it will allow readers without a background in biology to learn about this work and its revolutionary implications.